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What nature never thought to make.
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Most proteins 
are undruggable.

70% of drug targets are too complex for small molecules and beyond the reach of biologics. Until now.

01

Macrocycles

Nature’s solution 
to hard targets.

Small Molecules can permeate cells but cant bind complex targets. Biologics, like antibody therapeutics, can only act on targets displayed outside of cells.

 

Naturally derived macrocycles evolved to bridge the gap between small molecules and biologics by transcending the traditional boundaries of cell permeability to access deep, complex targets with high specificity.

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Big Biologics

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Medium
Macrocycles

Small
Molecules

 

02

Macrocycle Discovery Platform

From serendipity 
to  design.

Our AI-enhanced platform creates entirely new drugs by engineering synthetic molecules to mimic nature’s macrocycles. Our platform produces passively permeable, macrocyclic peptides that access and address traditionally undruggable targets.

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03

About

Unnatural Products for uncommon outcomes.

We’re a California-based biotech company using our platform to tackle the hard targets that will change the future of medicine.

 

Founded by macrocycle pioneers whose academic work uncovered how Nature’s macrocycles work, UNP is a team of passionate scientists, engineers, and experienced drug developers.

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VP of Platform

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Co-Founder & CSO

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Co-Founder & CEO

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VP Biology, Head of Translational Science

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Interim Head of Clinical Strategy

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Independent BoD & Senior BD Advisor

 

04

Careers

We’re looking for unconventional.

Crafting code. Manipulating molecules. Conquering mountains in life and in the lab.

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07

Our Partners

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08

Our Investors

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