Engineering the future of highly targeted peptides
Unlocking macrocyclic peptides for the most challenging drug targets, bridging the gap between small molecules and biologics.
Backed by world class investors and partners
Redefining drug discovery by accessing the “undruggable.”
Our platform combines parallel synthesis with proprietary machine learning to create drug-like macrocyclic peptides with optimized medicinal properties.
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Parallel Synthesis
Rapidly iterating through massive chemical space to identify high-affinity binders for challenging intracellular targets.
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Cell Permeability
Optimizing molecular properties using AI-driven insights to overcome cellular barriers and ensure intracellular delivery.
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ADME Profiling
Fine-tuning pharmacokinetics and metabolic stability to identify the most potent and safe clinical leads.
The Science
Born out of the Lokey Lab, the field leader in leader in macrocycles, UNP has created the the first platform to repeatably engineer synthetic macrocyclic peptides at scale.
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Our Vision & Team
We’re redefining what's possible in drug discovery by unlocking the therapeutic potential of synthetic macrocycles (unnatural products) to build a robust, diverse pipeline of valuable medicines.
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Careers
We're looking for scientists, engineers, and visionaries to help us unlock the potential of macrocyclic peptides.